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Englisch: intent-to-treat analysis

Deutsch translation: Auswertungsverfahren von klinischen Studien



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Glossareintrag (aus Frage unten abgeleitet)
Englisch Begriff oder Satz:intent-to-treat analysis
Deutsch Übersetzung:Auswertungsverfahren von klinischen Studien
Eingetragen von:Maya Jurt
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9:00pm Oct 27, 2000Login or register (free) for more options.
Übersetzungen Englisch > Deutsch [PRO]
Medical - Mathematik und Statistik
Englisch Begriff oder Satz: intent-to-treat analysis
in preparation for a clinical trial
Sigrid Junkermann
Vereinigte Staaten
more on intent to treat
Erklärung:
This analysis does not, as its name would seem to indicate, pertain to the analysis a treatment plan or of an intended treatment. Rather, it refers to the statistical evaluation of data from clinical studies. See below:

intent-to-treat analysis: (engl.) Auswertungsverfahren von klinischen Studien, bei dem alle Patienten berücksichtigt werden. Begleitmedikationen oder Noncompliance führen nicht zu einem Ausschluß von der Auswertung. Die Effektivität einer Therapie unter realistischen Bedingungen soll bewertet werden.
http://www.aidshilfe.de/

The method of including all randomized subject's data into an analysis, regardless of compliance, is know as an "intent-to-treat analysis". While it may seem logical to exclude non-compliant subjects, restricting the analysis to compliant subjects can lead to biased results. If non-compliance is in any way related to outcome, restricting analysis could misrepresent differences between treatment groups. If subjects are non-compliant due to failure to improve, side effects, or any other factor that is related to outcome, the result may be misrepresented. Although the intent-to-treat analysis is used by most clinical trials conducted today, there are times when it may not be appropriate. In situations involving treatment crossovers which were not planned, systematic, or incorporated into the study design, an intent-to-treat analysis may be inappropriate. The choice of statistical procedure depends upon the nature of the outcome variable. Regardless of the analytic approach, the better the subject compliance to the study procedures, the more reliable and valid the data will be.
http://www.researchpractice.com/cumulative/cum_jf98_1.shtml
Ausgewählte Antwort von:

Ulrike Lieder
Vereinigte Staaten
Hinweis von Fragesteller an den Antwortenden
Thanks Uel,
that sounds as if there is no short translation for it.
Regards
Sigrid

4 KudoZ-Punkte wurden für diese Antwort vergeben



ZUSAMMENFASSUNG ALLER ÜBERSETZUNGEN (DEUTSCH)
namore on intent to treatUlrike Lieder
naAnalyse des Behandlungsplanes oder der beabsichtigten Behandlung
Elisabeth Moser


  


Antworten

3 Stunden
Analyse des Behandlungsplanes oder der beabsichtigten Behandlung

Erklärung:
intent=jur. wahre Bedeutung, Sinn (Gesetz), Absicht--auch: Ziel, Zweck, Plan
you have to see what fits best your context. Contrary of the answer you got
on your first questionm, I would translate it.
Good luck,
Lis


    Muret-Sanders
Elisabeth Moser
Deutschland
Muttersprache: Deutsch
PRO-Punkte in Kategorie: 4

Kommentare zu dieser Antwort (und Antworten vom Beantworter der Frage)
Ulrike Lieder
-38 Min.
Login to enter a peer comment (or grade)


14 Stunden
more on intent to treat

Erklärung:
This analysis does not, as its name would seem to indicate, pertain to the analysis a treatment plan or of an intended treatment. Rather, it refers to the statistical evaluation of data from clinical studies. See below:

intent-to-treat analysis: (engl.) Auswertungsverfahren von klinischen Studien, bei dem alle Patienten berücksichtigt werden. Begleitmedikationen oder Noncompliance führen nicht zu einem Ausschluß von der Auswertung. Die Effektivität einer Therapie unter realistischen Bedingungen soll bewertet werden.
http://www.aidshilfe.de/

The method of including all randomized subject's data into an analysis, regardless of compliance, is know as an "intent-to-treat analysis". While it may seem logical to exclude non-compliant subjects, restricting the analysis to compliant subjects can lead to biased results. If non-compliance is in any way related to outcome, restricting analysis could misrepresent differences between treatment groups. If subjects are non-compliant due to failure to improve, side effects, or any other factor that is related to outcome, the result may be misrepresented. Although the intent-to-treat analysis is used by most clinical trials conducted today, there are times when it may not be appropriate. In situations involving treatment crossovers which were not planned, systematic, or incorporated into the study design, an intent-to-treat analysis may be inappropriate. The choice of statistical procedure depends upon the nature of the outcome variable. Regardless of the analytic approach, the better the subject compliance to the study procedures, the more reliable and valid the data will be.
http://www.researchpractice.com/cumulative/cum_jf98_1.shtml


Ulrike Lieder
Vereinigte Staaten
Muttersprache: Deutsch
PRO-Punkte in Kategorie: 4
Hinweis von Fragesteller an den Antwortenden
Thanks Uel,
that sounds as if there is no short translation for it.
Regards
Sigrid
Login to enter a peer comment (or grade)





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