mit äußerst flauer Absenkung im ADC-Map

English translation: with extremely low intensity in the ADC map

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase:mit äußerst flauer Absenkung im ADC-Map
English translation:with extremely low intensity in the ADC map
Entered by: Anne Schulz

18:38 Jul 5, 2009
German to English translations [PRO]
Medical - Medical (general) / radiology
German term or phrase: mit äußerst flauer Absenkung im ADC-Map
"In der Diffusionswichtung finden sich konkordant rechts occipital zwei kleine hyperintense Spots mit äußerst flauer Absenkung im ADC-Map."

Ich verstehe "mit äußerst flauer Absenkung im ADC-Map" nicht genau, erlaube mir aber nicht zu raten.

Ich wuerde es so uebersetzen:

"with very weakly decreased apparent difussion coefficient values in the ADC map"

Eine Alternative waere: "with very weak intensity in the ADC map." Das ist aber was anderes.

Help, please!
Lirka
Austria
Local time: 19:50
with extremely low intensity in the ADC map
Explanation:
Although the grammar seems to suggest the opposite, your second suggestion is probably appropriate.
For a hyperintense lesion on the diffusion weighted trace image, the corresponding ADC map should show hypointensity if it is a real diffusion pathology rather than an artifact.
Besides, "flau" is typically used to characterize a signal intensity. I therefore assume that this statement was meant as "Absenkung auf äußerst flaue Werte im ADC-Map".
(Contrarily, if the conclusion of the MRI report is that the patient has no "real" lesions, the interpretation of "flaue Absenkung" would be the opposite :-)

"ADC maps are acquired via post-processing by calculating the apparent diffusion coefficient for each voxel of tissue and allocating a signal intensity according to its value. Therefore restricted tissue, which has a low ADC, is darker than free diffusing areas that have a high ADC. The contrast is therefore the mirror of the trace images. This is useful when T2 shine through is a problem."
http://books.google.com/books?id=PZoaJek9u-oC&pg=PA375&lpg=P...


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Note added at 22 hrs (2009-07-06 17:35:40 GMT)
--------------------------------------------------

Re your note: Yes, exactly, a low diffusion coefficient (impaired diffusion in tissue, low ADC value) is represented by a low intensity signal in the ADC map, but a bright (hyperintense) signal in the diffusion-weighted trace image (the "normal" MRI image).
("Signal" actually being just an allocated brightness value in MRI.)
Selected response from:

Anne Schulz
Germany
Local time: 19:50
Grading comment
Thanks very much, Anne. This was a real challenge for me. I even contacted one of my former neuroradiology profs, but did not get an answer yet ( Urlaub :)). When I do, I'll post it here. Thanks again for your clear explanations, I think I understand the concept a bit better now.
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +2with extremely low intensity in the ADC map
Anne Schulz
3 +1extremely weak decrease in the ADC map
Gisela Greenlee
3completely stagnant values
Rosa Paredes
Summary of reference entries provided
"eingeschränkte Diffusion mit entsprechender Absenkung"
Susanne Schiewe
"with decreased ADC"
Audrey Foster (X)

Discussion entries: 10





  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5
completely stagnant values


Explanation:
IMO :)

Rosa Paredes
Canada
Local time: 13:50
Works in field
Native speaker of: Native in EnglishEnglish, Native in SpanishSpanish
PRO pts in category: 30
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5 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
extremely weak decrease in the ADC map


Explanation:
The way I understand it, it's the two hyperintense spots that demonstrate the weak decrease (of their hyperintensity) in the ADC map.

Gisela Greenlee
Local time: 12:50
Specializes in field
Native speaker of: German
PRO pts in category: 1195

Peer comments on this answer (and responses from the answerer)
agree  robin25
1 day 5 hrs
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11 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
with extremely low intensity in the ADC map


Explanation:
Although the grammar seems to suggest the opposite, your second suggestion is probably appropriate.
For a hyperintense lesion on the diffusion weighted trace image, the corresponding ADC map should show hypointensity if it is a real diffusion pathology rather than an artifact.
Besides, "flau" is typically used to characterize a signal intensity. I therefore assume that this statement was meant as "Absenkung auf äußerst flaue Werte im ADC-Map".
(Contrarily, if the conclusion of the MRI report is that the patient has no "real" lesions, the interpretation of "flaue Absenkung" would be the opposite :-)

"ADC maps are acquired via post-processing by calculating the apparent diffusion coefficient for each voxel of tissue and allocating a signal intensity according to its value. Therefore restricted tissue, which has a low ADC, is darker than free diffusing areas that have a high ADC. The contrast is therefore the mirror of the trace images. This is useful when T2 shine through is a problem."
http://books.google.com/books?id=PZoaJek9u-oC&pg=PA375&lpg=P...


--------------------------------------------------
Note added at 22 hrs (2009-07-06 17:35:40 GMT)
--------------------------------------------------

Re your note: Yes, exactly, a low diffusion coefficient (impaired diffusion in tissue, low ADC value) is represented by a low intensity signal in the ADC map, but a bright (hyperintense) signal in the diffusion-weighted trace image (the "normal" MRI image).
("Signal" actually being just an allocated brightness value in MRI.)

Anne Schulz
Germany
Local time: 19:50
Specializes in field
Native speaker of: German
PRO pts in category: 1611
Grading comment
Thanks very much, Anne. This was a real challenge for me. I even contacted one of my former neuroradiology profs, but did not get an answer yet ( Urlaub :)). When I do, I'll post it here. Thanks again for your clear explanations, I think I understand the concept a bit better now.
Notes to answerer
Asker: Thanks, Anne. I have found that hyperintense lesions have a corresponding decreased ADC ( indicating infarction). However, what I do not understand is the connection with the ADC value and signal intensity. Does a decreased ADC value mean a hypointense signal, or vice versa? In case you know...


Peer comments on this answer (and responses from the answerer)
agree  Susanne Schiewe: ich denke auch, dass hier die Absenkung der Signalstärke gemeint ist
13 mins
  -> Danke, Susanne!

agree  Marga Shaw
2 hrs
  -> Danke, Marga!
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Reference comments


1 hr
Reference: "eingeschränkte Diffusion mit entsprechender Absenkung"

Reference information:
http://books.google.com/books?id=ma1-waw2rkcC&pg=RA1-PA54&lp...

Low signal (arrows) on the ADC map confirms the acute nature of the diffusion changes.
http://www.medscape.com/viewarticle/500443_4

Susanne Schiewe
Germany
Specializes in field
Native speaker of: German
PRO pts in category: 848
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8 hrs
Reference: "with decreased ADC"

Reference information:
Search for the phrase "with decreased ADC" in the document here:
http://tinyurl.com/pz72td


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Note added at 8 hrs (2009-07-06 03:25:34 GMT)
--------------------------------------------------

Also, googling for "ADC map" + "hyperintense spots" may give some clues, hopefully ?

Audrey Foster (X)
Native speaker of: Native in EnglishEnglish
PRO pts in category: 12
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