Mar 10, 2010 11:49
14 yrs ago
1 viewer *
German term
Präfinal
German to English
Medical
Medical: Pharmaceuticals
Die letale Dosis beträgt bei Ratten ca. 400 mg/kg nach intravenöser Gabe, bei Hunden 400 — 500 mg/kg nach oraler Applikation. Beim Hund werden bei hohen Dosen Erbrechen, Speichelfluß und Sedation beobachtet. Präfinal treten tonisch-klonische Krämpfe auf.
Proposed translations
(English)
3 +6 | preceding death | Marga Shaw |
3 +3 | In the prefinal stage | Brita Fiess (X) |
4 | pre-terminal(ly) | casper (X) |
Proposed translations
+6
19 mins
Selected
preceding death
Präfinal = preceding death, pre-agonal, pre-agonic
http://books.google.com/books?id=Xuwh01IxikoC&pg=PA1213&lpg=...
For example:
There is no pain because the gradual pre-agonic and agonic changes in the biochemistry of the central nervous system dull the perception of pain and ...
http://books.google.com/books?id=ImntheG-aqcC&pg=PA46&lpg=PA...
Investigation into use of drugs preceding death from asthma.
http://www.bmj.com/cgi/content/abstract/1/5588/339
Additionally, there were reductions in the total synapsin/synaptophysin ratios in all three subject groups. Pre-agonal medication cannot entirely be ruled out in this study as an explanation for the findings; however, we did not observe changes in either synaptophysin or synapsin in the hippocampus following lithium or haloperidol treatment of rats.
http://www.nature.com/mp/journal/v7/n6/full/4001158a.html
--------------------------------------------------
Note added at 34 mins (2010-03-10 12:24:49 GMT)
--------------------------------------------------
In addition, both agents abolished the early seizure activity, suggesting that this first phase of seizures is due to cyanide and not the parent molecule. 1-Benzylimidazole did not prevent the severe clonic convulsive phase preceding death, suggesting that these terminal convulsions are due to the toxic effects of the parent AN molecule.
http://www.springerlink.com/content/v3vg834010661333/
In all dosage groups, females had decreased activity, bradypnea and ptosis with clonic convulsions preceding death; in males, ptosis was seen at all dose levels while tremors and clonic convulsions were seen at all but the lowest dose (771 mg/kg).
http://209.85.229.132/search?q=cache:Bc-BHN9Not8J:www.medici...
http://books.google.com/books?id=Xuwh01IxikoC&pg=PA1213&lpg=...
For example:
There is no pain because the gradual pre-agonic and agonic changes in the biochemistry of the central nervous system dull the perception of pain and ...
http://books.google.com/books?id=ImntheG-aqcC&pg=PA46&lpg=PA...
Investigation into use of drugs preceding death from asthma.
http://www.bmj.com/cgi/content/abstract/1/5588/339
Additionally, there were reductions in the total synapsin/synaptophysin ratios in all three subject groups. Pre-agonal medication cannot entirely be ruled out in this study as an explanation for the findings; however, we did not observe changes in either synaptophysin or synapsin in the hippocampus following lithium or haloperidol treatment of rats.
http://www.nature.com/mp/journal/v7/n6/full/4001158a.html
--------------------------------------------------
Note added at 34 mins (2010-03-10 12:24:49 GMT)
--------------------------------------------------
In addition, both agents abolished the early seizure activity, suggesting that this first phase of seizures is due to cyanide and not the parent molecule. 1-Benzylimidazole did not prevent the severe clonic convulsive phase preceding death, suggesting that these terminal convulsions are due to the toxic effects of the parent AN molecule.
http://www.springerlink.com/content/v3vg834010661333/
In all dosage groups, females had decreased activity, bradypnea and ptosis with clonic convulsions preceding death; in males, ptosis was seen at all dose levels while tremors and clonic convulsions were seen at all but the lowest dose (771 mg/kg).
http://209.85.229.132/search?q=cache:Bc-BHN9Not8J:www.medici...
4 KudoZ points awarded for this answer.
Comment: "Selected automatically based on peer agreement."
+3
3 mins
In the prefinal stage
...
Peer comment(s):
agree |
Rolf Keiser
6 mins
|
Thanks!
|
|
agree |
Tatyana Gardner
2 hrs
|
Thanks!
|
|
agree |
Harald Moelzer (medical-translator)
12 days
|
Thanks!
|
1 hr
Something went wrong...