Jun 17, 2015 15:36
8 yrs ago
German term
Ernteaufbau
German to English
Science
Medical: Pharmaceuticals
technical report on a cell culture batch
I'm translating a summary of sequence/batch-related deviations concerning a production report on fermentation and "Ernte" of a cell culture. I've found the verb "harvest" in relation to cell cultures, although I'm not sure what it means exactly in the context. Probably also because of this, I can't make sense of the word "Ernteaufbau". Here are some examples taken from the document:
- Der tatsächliche Ernteaufbau und die Erntedurchfuhrung ist entsprechend der Anlage x ausgeführt worden
- Der ordnungsgemäße Ernteaufbau wurde [...] abgestimmt und freigegeben
- Schemata des Ernteaufbaus mit zugehörigen Equipment- und Schlauchbezeichnungen
Any help at all will be greatly appreciated.
- Der tatsächliche Ernteaufbau und die Erntedurchfuhrung ist entsprechend der Anlage x ausgeführt worden
- Der ordnungsgemäße Ernteaufbau wurde [...] abgestimmt und freigegeben
- Schemata des Ernteaufbaus mit zugehörigen Equipment- und Schlauchbezeichnungen
Any help at all will be greatly appreciated.
Proposed translations
(English)
2 +2 | harvesting setup | Melanie Nassar |
3 +2 | harvest(ing) schedule | uyuni |
Proposed translations
+2
43 mins
Selected
harvesting setup
Or perhaps harvesting system, but "Schemata des Ernteaufbaus" indicates that it refers to the actual physical equipment, which may be more clear using setup.
layout or configuration are other options
Does not Google well, but there is this:
As such, this method facilitates the effective clarification of crude, high-density cell culture harvests in a single-use large-scale setup.
http://www.contractpharma.com/issues/2015-06-01/view_feature...
For heart valves in this case:
Applying this criteria in our harvesting setup limits
the availability of valves dramatically, and with this study we would like to see whether perfectly suitable
valves can in selective cases be harvested up to 48 hrs after death and beyond.
http://www.mrc.ac.za/cvdmd/section2.pdf
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Note added at 1 hr (2015-06-17 16:54:49 GMT)
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The Schemata in this case includes the designations of the equipment and tubing, so it seemed to me that it would most likely be a drawing. I suppose you could still use system in this case.
layout or configuration are other options
Does not Google well, but there is this:
As such, this method facilitates the effective clarification of crude, high-density cell culture harvests in a single-use large-scale setup.
http://www.contractpharma.com/issues/2015-06-01/view_feature...
For heart valves in this case:
Applying this criteria in our harvesting setup limits
the availability of valves dramatically, and with this study we would like to see whether perfectly suitable
valves can in selective cases be harvested up to 48 hrs after death and beyond.
http://www.mrc.ac.za/cvdmd/section2.pdf
--------------------------------------------------
Note added at 1 hr (2015-06-17 16:54:49 GMT)
--------------------------------------------------
The Schemata in this case includes the designations of the equipment and tubing, so it seemed to me that it would most likely be a drawing. I suppose you could still use system in this case.
Note from asker:
Thank you for your reply, why do you feel "Schemata" indicates that it refers to the physical equipment? As far as I understand it, Schema can refer to a system/procedure or maybe even an actual table/chart, the use of which is not necessarily limited to physical equipment. Could you please help me understand what you mean? |
Peer comment(s):
agree |
Anne Schulz
: Verstehe ich genauso: Aufbau = setup, Durchführung = procedure o. schedule, und die "Schemata" dürften Schemazeichnungen sein.
2 hrs
|
Danke, Anne
|
|
agree |
Harald Moelzer (medical-translator)
23 hrs
|
3 KudoZ points awarded for this answer.
Comment: "I chose to translate with "harvesting system" in the end, because I feel that could be used to refer both to the physical setup and to schedules/plan. "
+2
36 mins
harvest(ing) schedule
"Aufbau" akin "Ablaufplan" akin planning/organization/workflow/plan of procedures concerning the harvesting of cells from the culture(s), at least in my understanding...
The precise feeding and *harvesting schedule of cell cultures* performed with for different feeder cell lines or clones of them may need to be optimized following ...
https://books.google.de/books?id=z39tf6y_uF4C&pg=PA157&lpg=P...
Feeding and *harvesting schedule* depends on the cell line, the seeding density, and the target titer.
http://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=...
Further studies should verify the optimal *harvesting schedule*...
https://books.google.de/books?id=F7Jn7U2YxxMC&pg=PA64&lpg=PA...
*harvesting schedule* of Schmid and Linsenmayer was used...
http://www.jbc.org/content/263/1/581.full.pdf
*harvest schedule* can be modified in consultation with the investigator.
http://www.mdanderson.org/education-and-research/resources-f...
The precise feeding and *harvesting schedule of cell cultures* performed with for different feeder cell lines or clones of them may need to be optimized following ...
https://books.google.de/books?id=z39tf6y_uF4C&pg=PA157&lpg=P...
Feeding and *harvesting schedule* depends on the cell line, the seeding density, and the target titer.
http://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=...
Further studies should verify the optimal *harvesting schedule*...
https://books.google.de/books?id=F7Jn7U2YxxMC&pg=PA64&lpg=PA...
*harvesting schedule* of Schmid and Linsenmayer was used...
http://www.jbc.org/content/263/1/581.full.pdf
*harvest schedule* can be modified in consultation with the investigator.
http://www.mdanderson.org/education-and-research/resources-f...
Note from asker:
Thank you, I selected Melanie's answer because it made me notice an aspect I hadn't considered before, therefore being the most helpful, but since your translation and your sources are also convincing and I'm not 100 % sure, I've entered "harvesting system" in the glossary, which could refer to both the physical setup and to schedules/plan. |
Peer comment(s):
agree |
philgoddard
: Yes, and I agree with the alternatives you suggest in the first line of your answer.
13 mins
|
Thank you, Phil!
|
|
agree |
Jacek Konopka
: Excellent research. Just very professional.
19 hrs
|
Danke Dir, Jacek!
|
Discussion