nachteilig

English translation: (point 2) may detrimentally affect

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase:nachteilig
English translation:(point 2) may detrimentally affect
Entered by: Ellen Kraus

21:55 Feb 3, 2013
German to English translations [PRO]
Medical - Medical (general)
German term or phrase: nachteilig
Good evening!

I have a bit of a problem understanding the following in detail:

"Eine HRT, insbesondere eine kombinierte Behandlung mit Estrogenen und Gestagenen, führt zu einer erhöhten Brustdichte in der Mammographie, was sich nachteilig auf die radiologische Brustkrebsdiagnostik auswirken kann.
[HRT= hormone replacement therapy]

Now, we know that women with high breast density (as seen on a mammogram) are four to five times more likely to get breast cancer than women with low breast density.
At the same time, increased tissue density (eg in younger women) poses problems in accurate interpretation of mammography results.

My question: how should I understand 'nachteilig' here?
1. that women with high breast density have a more unfavorable (i.e. higher) risk of breast cancer
or
2. ( what I am thinking) that increased breast density complicates the imaging diagnostic work-up of breast cancer.

Thanks a lot for your insights!
Lirka
Austria
Local time: 11:22
(point 2) may detrimentally affect
Explanation:
may have a detrimental effect on
Selected response from:

Ellen Kraus
Austria
Local time: 11:22
Grading comment
Thanks!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +6may adversely affect
Marga Shaw
3 +5(point 2) may detrimentally affect
Ellen Kraus


Discussion entries: 4





  

Answers


11 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +5
(point 2) may detrimentally affect


Explanation:
may have a detrimental effect on

Ellen Kraus
Austria
Local time: 11:22
Specializes in field
Native speaker of: Native in GermanGerman
PRO pts in category: 341
Grading comment
Thanks!

Peer comments on this answer (and responses from the answerer)
agree  Nils Andersson: I was going to write "disadvantageous" etc. but the proposed version is better
35 mins
  -> thank you, Nils !

agree  David Tracey, PhD
5 hrs
  -> thank you, David !

agree  Harald Moelzer (medical-translator)
9 hrs
  -> thank you, Harald !

agree  David Moore (X)
12 hrs
  -> thank you, David !

agree  uyuni
15 hrs
  -> thank you, uyuni !
Login to enter a peer comment (or grade)

1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +6
may adversely affect


Explanation:
HRT may increase mammpgraphic density which can adverselt affect the detection/diagnosis of breast cancer

HRT, especially combined therapy, may increase mammographic
density, which may adversely affect radiological detection of
breast cancer.
https://docs.google.com/viewer?a=v&q=cache:cOCrcb3rW3YJ:www....

HRT, especially oestrogen-progestagen combined treatment, increases the density of mammographic
images which may adversely affect the radiological detection of breast cancer.
https://docs.google.com/viewer?a=v&q=cache:_Jn1TXAW3dEJ:www....



--------------------------------------------------
Note added at 1 hr (2013-02-03 23:19:46 GMT)
--------------------------------------------------

HRT, especially combined therapy, may increase mammographic density, which may adversely affect radiological detection of breast cancer. In the Women’s Health Initiative trial,13 [14] conjugated equine oestrogens (CEE) and CEE plus medroxyprogesterone increased the likelihood of having an abnormal mammogram that needed further evaluation.
http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CO...

HRT increases the density of mammographic images which may adversely affect the radiological detection of breast cancer in some case.
https://docs.google.com/viewer?a=v&q=cache:YchP0V2_7TYJ:www....


Marga Shaw
United Kingdom
Local time: 10:22
Specializes in field
Native speaker of: German
PRO pts in category: 700

Peer comments on this answer (and responses from the answerer)
agree  David Tracey, PhD
3 hrs
  -> Thank you David/

agree  BrigitteHilgner
7 hrs
  -> Thank you Brigitte.

agree  Harald Moelzer (medical-translator)
8 hrs
  -> Thank you Harald

agree  Steffen Walter
8 hrs
  -> Thank you Steffen.

agree  Cetacea
13 hrs
  -> Thank you Cetacea.

agree  Susanne Schiewe
17 hrs
  -> Thank you Susanne.
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